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1

How to Catch Moby Dick: Systematic Identification of Binding Partners for UNC-89 (Obscurin)

Qadota, Hiroshi, Xiong, Ge, Wilson, Kristy, Duran, M. Berenice, Swartzbaugh, Emily, Nahabedian, John, Benian, Guy

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 39 KB

english, 2011

2

RHO gene products, putative small GTP-binding proteins, are importnat for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae

Hiroshi Qadota, Isao Ishii, Asao Fujiyama, Yoshikazu Ohya, Yasuhiro Anraku

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 631 KB

english, 1992

3

Mutational analysis of theβ-subunit of yeast geranylgeranyl transferase I

Yoshikazu Ohya, Brian E. Caplin, Hiroshi Qadota, Michael F. Tibbetts, Yasuhiro Anraku, John R. Pringle, Mark S. Marshall

Journal:

Molecular Genetics and Genomics

Année:

1996

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1996

4

Molecular cloning and characterization ofDrosophilagenes encoding small GTPases of therabandrhofamilies

T. Sasamura, T. Kobayashi, S. Kojima, H. Qadota, Y. Ohya, I. Masai, Y. Hotta

Journal:

Molecular Genetics and Genomics

Année:

1997

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1997

5

Regulatory machinery of UNC-33 Ce-CRMP localization in neurites during neuronal development in Caenorhabditis elegans

Daisuke Tsuboi, Takao Hikita, Hiroshi Qadota, Mutsuki Amano, Kozo Kaibuchi

Journal:

Journal of Neurochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 758 KB

english, 2005

6

Efficient production of monoclonal antibodies recognizing specific structures in Caenorhabditis elegans embryos using an antigen subtraction method

Kazumasa Takeda, Chie Watanabe, Hiroshi Qadota, Momoyo Hanazawa, Asako Sugimoto

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 565 KB

english, 2008

7

C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin Adhesion Complexes

A.Craig Mackinnon, Hiroshi Qadota, Kenneth R. Norman, Donald G. Moerman, Benjamin D. Williams

Journal:

Current Biology

Année:

2002

Langue:

english

Fichier:

PDF, 487 KB

english, 2002

8

C. elegans PAT-6/Actopaxin Plays a Critical Role in the Assembly of Integrin Adhesion Complexes In Vivo

Xinyi Lin, Hiroshi Qadota, Donald G. Moerman, Benjamin D. Williams

Journal:

Current Biology

Année:

2003

Langue:

english

Fichier:

PDF, 545 KB

english, 2003

9

Isolation of the Interacting Molecules with GEX-3 by a Novel Functional Screening

Daisuke Tsuboi, Hiroshi Qadota, Katsuhisa Kasuya, Mutsuki Amano, Kozo Kaibuchi

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 167 KB

english, 2002

10

Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure

Takao Hikita, Hiroshi Qadota, Daisuke Tsuboi, Shinichiro Taya, Donald G. Moerman, Kozo Kaibuchi

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2005

11

Establishment of a tissue-specific RNAi system in C. elegans

Hiroshi Qadota, Makiko Inoue, Takao Hikita, Mathias Köppen, Jeffrey D. Hardin, Mutsuki Amano, Donald G. Moerman, Kozo Kaibuchi

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

12

The DH-PH Region of the Giant Protein UNC-89 Activates RHO-1 GTPase in Caenorhabditis elegans Body Wall Muscle

Hiroshi Qadota, Anne Blangy, Ge Xiong, Guy M. Benian

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2008

13

A LIM-9 (FHL) / SCPL-1 (SCP) Complex Interacts with the C-terminal Protein Kinase Regions of UNC-89 (Obscurin) in Caenorhabditis elegans Muscle

Ge Xiong, Hiroshi Qadota, Kristina B. Mercer, Lee Anne McGaha, Andres F. Oberhauser, Guy M. Benian

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 906 KB

english, 2009

14

Extensive and Modular Intrinsically Disordered Segments in C. elegans TTN-1 and Implications in Filament Binding, Elasticity and Oblique Striation

Jeffrey G. Forbes, Denise B. Flaherty, Kan Ma, Hiroshi Qadota, Guy M. Benian, Kuan Wang

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 4.20 MB

english, 2010

15

α-Actinin Is Required for the Proper Assembly of Z-Disk/Focal-Adhesion-Like Structures and for Efficient Locomotion in Caenorhabditis elegans

Gary L. Moulder, Gina H. Cremona, Janet Duerr, Jeffrey N. Stirman, Stephen D. Fields, Wendy Martin, Hiroshi Qadota, Guy M. Benian, Hang Lu, Robert J. Barstead

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2010

16

PKN-1, a Homologue of Mammalian PKN, Is Involved in the Regulation of Muscle Contraction and Force Transmission in C. elegans

Hiroshi Qadota, Takayuki Miyauchi, John F. Nahabedian, Jeffrey N. Stirman, Hang Lu, Mutsuki Amano, Guy M. Benian, Kozo Kaibuchi

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2011

17

The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6

Miwa Furuya, Hiroshi Qadota, Andrew D. Chisholm, Asako Sugimoto

Journal:

Developmental Biology

Année:

2005

Langue:

english

Fichier:

PDF, 784 KB

english, 2005

18

UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle

Kenneth R. Norman, Shaun Cordes, Hiroshi Qadota, Poupak Rahmani, Donald G. Moerman

Journal:

Developmental Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2007

19

Bending amplitude – A new quantitative assay of C. elegans locomotion: Identification of phenotypes for mutants in genes encoding muscle focal adhesion components

John F. Nahabedian, Hiroshi Qadota, Jeffrey N. Stirman, Hang Lu, Guy M. Benian

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2012

20

Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase

von Castelmur, E., Strumpfer, J., Franke, B., Bogomolovas, J., Barbieri, S., Qadota, H., Konarev, P. V., Svergun, D. I., Labeit, S., Benian, G. M., Schulten, K., Mayans, O.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2012

21

Identification of Yeast Rho1p GTPase as a Regulatory Subunit of 1,3-beta -Glucan Synthase

Qadota, H., Python, C. P., Inoue, S. B., Arisawa, M., Anraku, Y., Zheng, Y., Watanabe, T., Levin, D. E., Ohya, Y.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 497 KB

english, 1996

22

Stretching of Twitchin Kinase

Strumpfer, Johan A., von Castelmur, Eleonore, Franke, Barbara, Barbieri, Sonia, Bogomolovas, Julijus, Qadota, Hiroshi, Konarv, Petr, Svergun, Dmitri, Labeit, Siegfried, Schulten, Klaus, Benian, Guy M.

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 58 KB

english, 2012

23

UNC-98 Links an Integrin-Associated Complex to Thick Filaments in Caenorhabditis elegans Muscle

Rachel K. Miller, Hiroshi Qadota, Megan L. Landsverk, Kristina B. Mercer, Henry F. Epstein and Guy M. Benian

Journal:

The Journal of Cell Biology

Année:

2006

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2006

24

Activation of Yeast Protein Kinase C by Rho1 GTPase

Journal:

Journal of Biological Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 723 KB

english, 1996

25

Conditional Lethality of a Yeast Strain Expressing Human RHOA in Place of RHO1

Hiroshi Qadota, Yasuhiro Anraku, David Botstein and Yoshikazu Ohya

Journal:

Proceedings of the National Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1994

26

Suppressor Mutations Suggest a Surface on PAT-4 (Integrin-linked Kinase) That Interacts with UNC-112 (Kindlin)

Qadota, H., Luo, Y., Matsunaga, Y., Park, A. S., Gernert, K. M., Benian, G. M.

Journal:

Journal of Biological Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 4.30 MB

english, 2014

27

Yeast 1,3- -Glucan Synthase Activity Is Inhibited by Phytosphingosine Localized to the Endoplasmic Reticulum

Abe, M., Nishida, I., Minemura, M., Qadota, H., Seyama, Y., Watanabe, T., Ohya, Y.

Journal:

Journal of Biological Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 743 KB

english, 2001

28

A Molecular Mechanism for the Requirement of PAT-4 (Integrin-linked Kinase (ILK)) for the Localization of UNC-112 (Kindlin) to Integrin Adhesion Sites

Qadota, H., Moerman, D. G., Benian, G. M.

Journal:

Journal of Biological Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2012

29

Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p.

Ohya, Y., Qadota, H., Anraku, Y., Pringle, J. R., Botstein, D.

Journal:

Molecular Biology of the Cell

Année:

1993

Langue:

english

Fichier:

PDF, 2.08 MB

english, 1993

30

A Novel Protein Phosphatase is a Binding Partner for the Protein Kinase Domains of UNC-89 (Obscurin) in Caenorhabditis elegans

Qadota, H., McGaha, L. A., Mercer, K. B., Stark, T. J., Ferrara, T. M., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2008

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2008

31

UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans

Wilson, K. J., Qadota, H., Mains, P. E., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2012

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2012

32

Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle

Matsunaga, Y., Qadota, H., Furukawa, M., Choe, H., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2015

Langue:

english

Fichier:

PDF, 2.46 MB

english, 2015

33

ZYX-1, the unique zyxin protein of Caenorhabditis elegans, is involved in dystrophin-dependent muscle degeneration

Lecroisey, C., Brouilly, N., Qadota, H., Mariol, M.-C., Rochette, N. C., Martin, E., Benian, G. M., Segalat, L., Mounier, N., Gieseler, K.

Journal:

Molecular Biology of the Cell

Année:

2013

Langue:

english

Fichier:

PDF, 4.00 MB

english, 2013

34

CSN-5, a Component of the COP9 Signalosome Complex, Regulates the Levels of UNC-96 and UNC-98, Two Components of M-lines in Caenorhabditis elegans Muscle

Miller, R. K., Qadota, H., Stark, T. J., Mercer, K. B., Wortham, T. S., Anyanful, A., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2009

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2009

35

Prenylation of Rho1p Is Required for Activation of Yeast 1,3- -Glucan Synthase

Inoue, S. B., Qadota, H., Arisawa, M., Watanabe, T., Ohya, Y.

Journal:

Journal of Biological Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 670 KB

english, 1999

36

Complementing Yeast rho1 Mutation Groups with Distinct Functional Defects

Saka, A., Abe, M., Okano, H., Minemura, M., Qadota, H., Utsugi, T., Mino, A., Tanaka, K., Takai, Y., Ohya, Y.

Journal:

Journal of Biological Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 778 KB

english, 2001

37

UNC-98 links an integrin-associated complex to thick filaments in Caenorhabditis elegans muscle

Miller, R. K., Qadota, H., Landsverk, M. L., Mercer, K. B., Epstein, H. F., Benian, G. M.

Journal:

The Journal of Cell Biology

Année:

2006

Langue:

english

Fichier:

PDF, 3.35 MB

english, 2006

38

UNC-98 and UNC-96 Interact with Paramyosin to Promote Its Incorporation into Thick Filaments of Caenorhabditis elegans

Miller, R. K., Qadota, H., Mercer, K. B., Gernert, K. M., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2008

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2008

39

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans

Warner, A., Xiong, G., Qadota, H., Rogalski, T., Vogl, A. W., Moerman, D. G., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2013

Langue:

english

Fichier:

PDF, 5.91 MB

english, 2013

40

Two LIM Domain Proteins and UNC-96 Link UNC-97/PINCH to Myosin Thick Filaments in Caenorhabditis elegans Muscle

Qadota, H., Mercer, K. B., Miller, R. K., Kaibuchi, K., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2007

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2007

41

The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viability

Warner, A., Qadota, H., Benian, G. M., Vogl, A. W., Moerman, D. G.

Journal:

Molecular Biology of the Cell

Année:

2011

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2011

42

Multiple Functional Domains of the Yeast l,3- -Glucan Synthase Subunit Fks1p Revealed by Quantitative Phenotypic Analysis of Temperature-Sensitive Mutants

Okada, H., Abe, M., Asakawa-Minemura, M., Hirata, A., Qadota, H., Morishita, K., Ohnuki, S., Nogami, S., Ohya, Y.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 2.87 MB

english, 2010

43

Molecular Structure of Sarcomere-to-Membrane Attachment at M-Lines in C. elegans Muscle

Qadota, Hiroshi, Benian, Guy M.

Journal:

Journal of Biomedicine and Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2010

44

An approach for exploring interaction between two proteins in vivo

Qadota, Hiroshi, Benian, Guy M.

Journal:

Frontiers in Physiology

Année:

2014

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2014

45

Ultra-structural time-course study in the C. elegans model for Duchenne muscular dystrophy highlights a crucial role for sarcomere-anchoring structures and sarcolemma integrity in the earliest steps of the muscle degeneration process

Brouilly, Nicolas, Lecroisey, Claire, Martin, Edwige, Pierson, Laura, Mariol, Marie-Christine, Qadota, Hiroshi, Labouesse, Michel, Streichenberger, Nathalie, Mounier, Nicole, Gieseler, Kathrin

Journal:

Human Molecular Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2015

46

Lack of GTP-Bound Rho1p in Secretory Vesicles of Saccharomyces cerevisiae

Mitsuhiro Abe, Hiroshi Qadota, Aiko Hirata and Yoshikazu Ohya

Journal:

The Journal of Cell Biology

Année:

2003

Langue:

english

Fichier:

PDF, 4.63 MB

english, 2003

47

ROM7/BEM4 encodes a novel protein that interacts with the Rho1p small GTP-binding protein in Saccharomyces cerevisiae.

Hirano, H, Tanaka, K, Ozaki, K, Imamura, H, Kohno, H, Hihara, T, Kameyama, T, Hotta, K, Arisawa, M, Watanabe, T, Qadota, H, Ohya, Y, Takai, Y

Journal:

Molecular and Cellular Biology

Année:

1996

Langue:

english

Fichier:

PDF, 757 KB

english, 1996

48

Conditional lethality of a yeast strain expressing human RHOA in place of RHO1.

Qadota, H., Anraku, Y., Botstein, D., Ohya, Y.

Journal:

Proceedings of the National Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1994

49

The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle

Qadota, H., Mayans, O., Matsunaga, Y., McMurry, J. L., Wilson, K. J., Kwon, G. E., Stanford, R., Deehan, K., Tinley, T. L., Ngwa, V. M., Benian, G. M.

Journal:

Molecular Biology of the Cell

Année:

2016

Langue:

english

Fichier:

PDF, 4.65 MB

english, 2016

50

Twitchin Kinase Inhibits Muscle Activity

Matsunaga, Yohei, Hwang, Hyundoo, Franke, Barbara, Williams, Rhys, Penley, McKenna, Qadota, Hiroshi, Yi, Hong, Morran, Levi T., Lu, Hang, Mayans, Olga, Benian, Guy M., Blanchoin, Laurent

Journal:

Molecular Biology of the Cell

Année:

2017

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2017